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New research/ Prebiotic dietary fibre may support emotional
Created on 2024.10.16
A new study, conducted by Jackson et al., demonstrates that the intake of the prebiotic dietary fibre oligofructose alone, or in combination with the human milk oligosaccharide 2’fucosyllactose, promotes a significant increase in Bifidobacteria in the gut and can result in substantial improvements in mood in healthy adults with mild to moderate feelings of anxiety and depression.
Two out of three consumers across the globe already see the importance of their gut on mood, saying that their digestive health has an influence on their mental wellbeing and stress levels. Thanks to the gut-brain axis, important mood parameters can be influenced via microbiota modulation. With mental health disorders such as anxiety and depression an increasing burden to the health systems globally, using a diet-approach that positively influences microbiota using gut-friendly food is an attractive proposition for decreasing public health costs and supporting healthy living.
The study, which ran over five weeks (1 week run-in and 4 weeks intervention), aimed to look at the effect of the chicory root fibre oligofructose and the human milk oligosaccharide 2’fucosyllactose on intestinal colonisation and their ability to reduce anxiety and depression. The 92 subjects chosen for the study were healthy and had mild to moderate levels of anxiety and depression. Using a randomised, double blind, placebo-controlled, parallel designed methodology, the subjects were split into four groups of 23 and given either 8g of oligofructose plus 2g of maltodextrin per day, 8g of oligofructose plus 2g of 2’fucosyllactose per day, 2g of 2’fucosyllactose plus 8g of maltodextrin per day, or 10g of maltodextrin per day.
At the end of the four-week intervention period, participants who consumed prebiotic oligofructose alone or in combination with 2’fucosyllactose showed significant increases in beneficial gut bacteria, including Bifidobacterium, Bacteroides, Roseburia, and Faecalibacterium prausnitzii, compared to the control group. Moreover, those who took oligofructose alone or in combination with 2’fucosyllactose also demonstrated significant improvements in various mood state parameters compared to the control group.
Commenting on the findings, Dr. Stephan Theis, Head of Nutrition Science at BENEO, said: "Thanks to this study, an important piece of scientific evidence has been contributed to the fascinating science of the gut-brain-axis. The results add to the growing body of evidence showing that the composition of gut microbiota and resulting metabolites impact mood state. The findings also demonstrate that targeted influence with prebiotics may be a viable way to improve mood. It is notable that oligofructose has once again been shown to have a significant effect on beneficial microbiota and is an essential contributor to the beneficial effects on gut microbiota and mood parameters when combined with 2’fucosyllactose."
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- Inulin
- Oligofructose
- Beta-glucan
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